Christopher Fritschi

机构：University of Pennsylvania · ORCID：0000-0002-7724-8130

发表论文 10 篇 · 总被引 57 次 · h-index 4

代表论文

• Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity (2023 · Proceedings of the National Academy of Sciences · 被引 31)
• Membrane HIV-1 envelope glycoproteins stabilized more strongly in a pretriggered conformation than natural virus Envs (2024 · iScience · 被引 8)
• Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics (2021 · ACS Medicinal Chemistry Letters · 被引 8)
• V3 tip determinants of susceptibility to inhibition by CD4-mimetic compounds in natural clade A human immunodeficiency virus (HIV-1) envelope glycoproteins (2023 · Journal of Virology · 被引 7)
• Structural and Functional Characterization of Indane-Core CD4-Mimetic Compounds Substituted with Heterocyclic Amines (2022 · ACS Medicinal Chemistry Letters · 被引 3)
• 8.2 – 00072 Early intervention with an indoline CD4-mimetic compound that sensitizes HIV-1-infected cells to ADCC favors post-treatment HIV control in humanized mice (2024 · Journal of Virus Eradication)