Joseph B. Bolen

发表论文 208 篇 · 总被引 21274 次 · h-index 76

代表论文

• An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer (2009 · Nature · 被引 2049)
• Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ (2010 · Molecular Cell · 被引 473)
• Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase (2007 · Proceedings of the National Academy of Sciences · 被引 420)
• MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-κB–dependent lymphoma (2010 · Blood · 被引 327)
• Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays (2011 · Clinical Cancer Research · 被引 309)
• Safety Evaluation of Lipid Nanoparticle–Formulated Modified mRNA in the Sprague-Dawley Rat and Cynomolgus Monkey (2017 · Veterinary Pathology · 被引 193)