Ira Pastan

机构：National Institutes of Health, National Cancer Institute · ORCID：0000-0002-9223-0270

发表论文 1612 篇 · 总被引 108705 次 · h-index 165

代表论文

• Tumor resistance to anti-mesothelin CAR-T cells caused by binding to shed mesothelin is overcome by targeting a juxtamembrane epitope (2024 · Proceedings of the National Academy of Sciences · 被引 27)
• A Bispecific Antibody That Targets the Membrane-Proximal Region of Mesothelin and Retains High Anticancer Activity in the Presence of Shed Mesothelin (2024 · Molecular Cancer Therapeutics · 被引 11)
• Complete Response in Hairy Cell Leukemia to Anti-CD22 CAR T-Cell Therapy (2025 · JCO Precision Oncology · 被引 2)
• A new treatment for canine B-cell lymphoma based on a recombinant single-domain antibody immunotoxin derived from Pseudomonas aeruginosa exotoxin A (2025 · Frontiers in Veterinary Science · 被引 2)
• Mapping drug distribution using CT imaging following direct tissue injection in ex vivo liver: informing clinical implementation (2025 · CVIR Oncology · 被引 1)
• Analysis of systemic immune changes in patients with advanced cancer treated with immunotoxin LMB-100 and tofacitinib. (2023 · Journal of Clinical Oncology · 被引 1)