Zhuanchang Wu

机构：Shandong University, Shandong Special Equipment Inspection Institute · ORCID：0000-0003-3940-3141

发表论文 49 篇 · 总被引 1475 次 · h-index 23

代表论文

• Palmitoylation of TIM-3 promotes immune exhaustion and restrains antitumor immunity (2024 · Science Immunology · 被引 86)
• Early life gut microbiota sustains liver-resident natural killer cells maturation via the butyrate-IL-18 axis (2023 · Nature Communications · 被引 64)
• Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance (2024 · Cell Reports Medicine · 被引 58)
• Identification of a small-molecule Tim-3 inhibitor to potentiate T cell–mediated antitumor immunotherapy in preclinical mouse models (2023 · Science Translational Medicine · 被引 55)
• TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis (2023 · Cell Death and Disease · 被引 46)
• Increased Siglec-9/Siglec-9L interactions on NK cells predict poor HCC prognosis and present a targetable checkpoint for immunotherapy (2024 · Journal of Hepatology · 被引 38)