Ion Cristian Cirstea

机构：Universität Ulm, University Hospital Ulm, Technische Hochschule Ulm · ORCID：0000-0003-3204-1598

发表论文 42 篇 · 总被引 1456 次 · h-index 17

代表论文

• Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis (2014 · Human Molecular Genetics · 被引 143)
• Dominant Noonan syndrome-causing LZTR1 mutations specifically affect the Kelch domain substrate-recognition surface and enhance RAS-MAPK signaling (2018 · Human Molecular Genetics · 被引 102)
• Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes (2012 · Human Molecular Genetics · 被引 48)
• Functional Cross-talk between Ras and Rho Pathways (2014 · Journal of Biological Chemistry · 被引 36)
• Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues (2023 · Communications Biology · 被引 35)
• ACE2-EGFR-MAPK signaling contributes to SARS-CoV-2 infection (2023 · Life Science Alliance · 被引 32)