Joel L. Sussman

机构：Weizmann Institute of Science · ORCID：0000-0003-0306-3878

发表论文 509 篇 · 总被引 36310 次 · h-index 92

代表论文

Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration (2018 · Chemistry - A European Journal · 被引 72)
Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3 (2019 · European Journal of Medicinal Chemistry · 被引 66)
Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents (2018 · Journal of Medicinal Chemistry · 被引 63)
The future of integrated structural biology (2024 · Structure · 被引 55)
Novel multitarget-directed ligands targeting acetylcholinesterase and σ1 receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase (2018 · European Journal of Medicinal Chemistry · 被引 52)
Enzyme Evolution: An Epistatic Ratchet versus a Smooth Reversible Transition (2019 · Molecular Biology and Evolution · 被引 44)