John G. Houston

发表论文 31 篇 · 总被引 933 次 · h-index 9

代表论文

ARV-110: An oral androgen receptor PROTAC degrader for prostate cancer. (2019 · Journal of Clinical Oncology · 被引 215)
Oral Estrogen Receptor PROTAC Vepdegestrant (ARV-471) Is Highly Efficacious as Monotherapy and in Combination with CDK4/6 or PI3K/mTOR Pathway Inhibitors in Preclinical ER+ Breast Cancer Models (2024 · Clinical Cancer Research · 被引 193)
Abstract P5-04-18: ARV-471, an oral estrogen receptor PROTAC degrader for breast cancer (2019 · Cancer Research · 被引 135)
Abstract 44: The discovery of ARV-471, an orally bioavailable estrogen receptor degrading PROTAC for the treatment of patients with breast cancer (2021 · Cancer Research · 被引 116)
Preclinical Evaluation of Bavdegalutamide (ARV-110), a Novel PROteolysis TArgeting Chimera Androgen Receptor Degrader (2024 · Molecular Cancer Therapeutics · 被引 88)
Abstract 43: Discovery of ARV-110, a first in class androgen receptor degrading PROTAC for the treatment of men with metastatic castration resistant prostate cancer (2021 · Cancer Research · 被引 76)