Thomas Sears

机构：Northwestern University, Neurological Surgery, Robert H. Lurie Comprehensive Cancer Center of Northwestern University · ORCID：0000-0003-3834-2439

发表论文 34 篇 · 总被引 260 次 · h-index 9

代表论文

• Postoperative risk of IDH mutant glioma–associated seizures and their potential management with IDH mutant inhibitors (2023 · Journal of Clinical Investigation · 被引 53)
• Modeling Therapy-Driven Evolution of Glioblastoma with Patient-Derived Xenografts (2022 · Cancers · 被引 17)
• Dynamic release of extracellular particles after opening of the blood-brain barrier predicts glioblastoma susceptibility to paclitaxel (2025 · Nature Communications · 被引 10)
• The novel DNA cross-linking agent KL-50 is active against patient-derived models of new and recurrent post-temozolomide mismatch repair-deficient glioblastoma (2024 · Neuro-Oncology · 被引 10)
• Panobinostat Effectively Increases Histone Acetylation and Alters Chromatin Accessibility Landscape in Canine Embryonic Fibroblasts but Does Not Enhance Cellular Reprogramming (2021 · Frontiers in Veterinary Science · 被引 7)
• R132H IDH1 sensitizes glioma to the antiproliferative and cytotoxic effects of BET inhibition (2022 · Journal of Cancer Research and Clinical Oncology · 被引 5)