Holly B. Kordasiewicz

机构：Ionis Pharmaceuticals (United States) · ORCID：0009-0004-0945-0769

发表论文 111 篇 · 总被引 8343 次 · h-index 39

代表论文

• Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial (2023 · Nature Medicine · 被引 354)
• α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson’s disease (2021 · JCI Insight · 被引 150)
• The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration (2020 · Nucleic Acids Research · 被引 129)
• Antisense Drugs Make Sense for Neurological Diseases (2020 · The Annual Review of Pharmacology and Toxicology · 被引 115)
• Exploratory Tau Biomarker Results From a Multiple Ascending-Dose Study of BIIB080 in Alzheimer Disease (2023 · JAMA Neurology · 被引 111)
• Alternative processing of human HTT mRNA with implications for Huntington’s disease therapeutics (2022 · Brain · 被引 63)