Duane R. Reiss

机构：Merck & Co., Inc., Rahway, NJ, USA (United States)

发表论文 42 篇 · 总被引 2492 次 · h-index 24

代表论文

• Discovery of the Dual Orexin Receptor Antagonist [(7 R )-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2 H -1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the Treatment of Insomnia (2010 · Journal of Medicinal Chemistry · 被引 379)
• Promotion of Sleep by Suvorexant—A Novel Dual Orexin Receptor Antagonist (2011 · Journal of Neurogenetics · 被引 270)
• In Vitro and in Vivo Evaluation of Dihydropyrimidinone C-5 Amides as Potent and Selective α1A Receptor Antagonists for the Treatment of Benign Prostatic Hyperplasia (2000 · Journal of Medicinal Chemistry · 被引 224)
• A peripherally acting alpha-2 adrenoceptor antagonist: L-659,066. (1988 · Journal of Pharmacology and Experimental Therapeutics · 被引 136)
• Pharmacological characterization of MK-6096 – A dual orexin receptor antagonist for insomnia (2011 · Neuropharmacology · 被引 127)
• Discovery of [(2R,5R)‐5‐{[(5‐Fluoropyridin‐2‐yl)oxy]methyl}‐2‐methylpiperidin‐1‐yl][5‐methyl‐2‐(pyrimidin‐2‐yl)phenyl]methanone (MK‐6096): A Dual Orexin Receptor Antagonist with Potent Sleep‐Promoting Properties (2012 · ChemMedChem · 被引 126)