Juan Dubrot

机构：Broad Institute, Harvard University, Massachusetts General Hospital, Clinica Universidad de Navarra, Center for Cancer Research, Universidad de Navarra · ORCID：0000-0002-8093-2208

发表论文 103 篇 · 总被引 4293 次 · h-index 31

代表论文

• In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer (2022 · Nature Immunology · 被引 233)
• In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma (2021 · Immunity · 被引 94)
• MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell–Suppressive Functions (2021 · Cancer Immunology Research · 被引 88)
• Macroautophagy in lymphatic endothelial cells inhibits T cell–mediated autoimmunity (2021 · The Journal of Experimental Medicine · 被引 35)
• Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening (2023 · Nature Communications · 被引 28)
• Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint (2024 · Immunity · 被引 26)