Darryl B. McConnell

机构：Boehringer Ingelheim (Austria) · ORCID：0000-0002-2537-3458

发表论文 171 篇 · 总被引 5112 次 · h-index 33

代表论文

• NMR-driven structure-based drug discovery by unveiling molecular interactions (2025 · Communications Chemistry · 被引 18)
• Discovery and Characterization of Brigimadlin, a Novel and Highly Potent MDM2–p53 Antagonist Suitable for Intermittent Dose Schedules (2024 · Molecular Cancer Therapeutics · 被引 18)
• Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent In Vivo Activities in Mouse Models of Hematological and Solid Tumors (2024 · Journal of Medicinal Chemistry · 被引 18)
• Chasing Red Herrings: Palladium Metal Salt Impurities Feigning KRAS Activity in Biochemical Assays (2024 · Journal of Medicinal Chemistry · 被引 13)
• Probing Protein–Ligand Methyl−π Interaction Geometries through Chemical Shift Measurements of Selectively Labeled Methyl Groups (2024 · Journal of Medicinal Chemistry · 被引 6)
• Discovery of Macrocyclic Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors that Demonstrate Potent Cellular Efficacy and In Vivo Activity in a Mouse Solid Tumor Xenograft Model (2025 · Journal of Medicinal Chemistry · 被引 5)