Sheng Tian

机构：Soochow University, Huazhong Agricultural University, Soochow University, Precision Therapeutics (United States), Drug Discovery Laboratory (Norway) · ORCID：0000-0003-4767-6262

发表论文 112 篇 · 总被引 5716 次 · h-index 35

代表论文

• FDW028, a novel FUT8 inhibitor, impels lysosomal proteolysis of B7-H3 via chaperone-mediated autophagy pathway and exhibits potent efficacy against metastatic colorectal cancer (2023 · Cell Death and Disease · 被引 61)
• Targeting P2Y14R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis (2024 · Nature Communications · 被引 40)
• Design and Characterization of a Novel eEF2K Degrader with Potent Therapeutic Efficacy Against Triple‐Negative Breast Cancer (2023 · Advanced Science · 被引 21)
• Structure-based virtual screening for discovery of paederosidic acid from Paederia scandens as novel P2Y14R antagonist (2023 · Phytomedicine · 被引 10)
• Identification of a Novel Substrate for eEF2K and the AURKA‐SOX8 as the Related Pathway in TNBC (2025 · Advanced Science · 被引 8)
• Structure–Activity Relationship Studies of Substituted 2-Phenyl-1,2,4-triazine-3,5(2 H ,4 H )-dione Analogues: Development of Potent eEF2K Degraders against Triple-Negative Breast Cancer (2024 · Journal of Medicinal Chemistry · 被引 8)