Sandrine Vendeville

机构：IPCOS (Belgium)

发表论文 41 篇 · 总被引 1275 次 · h-index 21

代表论文

• Discovery and Development of Simeprevir (TMC435), a HCV NS3/4A Protease Inhibitor (2014 · Journal of Medicinal Chemistry · 被引 215)
• Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor (2017 · Nature Communications · 被引 98)
• TMC647055, a Potent Nonnucleoside Hepatitis C Virus NS5B Polymerase Inhibitor with Cross-Genotypic Coverage (2012 · Antimicrobial Agents and Chemotherapy · 被引 46)
• Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055 (2012 · Bioorganic & Medicinal Chemistry Letters · 被引 39)
• Discovery and Early Development of TMC647055, a Non-Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase (2013 · Journal of Medicinal Chemistry · 被引 37)
• Structure‐Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties (2012 · Angewandte Chemie International Edition · 被引 37)