Darren G. Monckton

机构：University of Glasgow · ORCID：0000-0002-8298-8264

发表论文 191 篇 · 总被引 7617 次 · h-index 45

代表论文

Genetic modifiers of Huntington disease differentially influence motor and cognitive domains (2022 · The American Journal of Human Genetics · 被引 123)
Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset (2022 · Nature Neuroscience · 被引 94)
Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington’s disease decades before clinical motor diagnosis (2025 · Nature Medicine · 被引 73)
Genetic modifiers of somatic expansion and clinical phenotypes in Huntington’s disease highlight shared and tissue-specific effects (2025 · Nature Genetics · 被引 56)
Antisense oligonucleotide–mediated MSH3 suppression reduces somatic CAG repeat expansion in Huntington’s disease iPSC–derived striatal neurons (2025 · Science Translational Medicine · 被引 42)
Huntington disease: somatic expansion, pathobiology and therapeutics (2025 · Nature Reviews Neurology · 被引 25)