Binhua Lv

机构：Jiangsu T-mab BioPharma (China), Centre for Applied Psychology, Environmental and Social Research · ORCID：0000-0002-2006-2554

发表论文 26 篇 · 总被引 368 次 · h-index 11

代表论文

• EGT1442, a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA1c levels in db/db mice and prolongs the survival of stroke-prone rats (2011 · Pharmacological Research · 被引 76)
• Design, Synthesis, and Biological Evaluation of Deuterated C-Aryl Glycoside as a Potent and Long-Acting Renal Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes (2014 · Journal of Medicinal Chemistry · 被引 65)
• Exploration of O-spiroketal C-arylglucosides as novel and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors (2009 · Bioorganic & Medicinal Chemistry Letters · 被引 37)
• C-Aryl glucosides substituted at the 4′-position as potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes (2011 · Bioorganic & Medicinal Chemistry Letters · 被引 33)
• A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Ascending Dose and Food Effect Study to Evaluate the Tolerance, Pharmacokinetics of Jaktinib, a New Selective Janus Kinase Inhibitor in Healthy Chinese Volunteers (2020 · Frontiers in Pharmacology · 被引 28)
• ortho-Substituted C-aryl glucosides as highly potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors (2010 · Bioorganic & Medicinal Chemistry · 被引 23)