Sharon L. Hyzy

机构：Biogen (United States)

发表论文 111 篇 · 总被引 4808 次 · h-index 33

代表论文

• A CD45-targeted antibody-drug conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation in mice (2022 · Blood · 被引 49)
• Clearing and replacing tissue-resident myeloid cells with an anti-CD45 antibody–drug conjugate (2023 · Blood Advances · 被引 11)
• Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate–conditioned Fanconi anemia mice (2024 · Blood · 被引 10)
• A phase 1/2 study of donor-derived anti-CD33 CAR T-cell therapy (VCAR33) for relapsed/refractory AML after allogeneic HCT (2026 · Blood · 被引 5)
• A single dose of a CD137 antibody–drug conjugate protects rhesus macaque allogeneic HCT recipients against acute GVHD (2025 · Blood · 被引 5)
• A CD33-Deleted Allograft (Trem-cel) Enables Post-Hematopoietic Cell Transplant (HCT) Maintenance Dosing of Gemtuzumab Ozogamicin (GO) with Therapeutic Levels of Drug Exposure and Low Hematologic and Hepatic Toxicity in Patients with High-Risk Acute Myeloid Leukemia (AML) (2024 · Blood · 被引 5)