Tracy Zimmermann
机构:Alnylam Pharmaceuticals (United States)
发表论文 17 篇 · 总被引 6200 次 · h-index 13
代表论文
- RNAi-mediated gene silencing in non-human primates (2006 · Nature · 被引 1350)
- A combinatorial library of lipid-like materials for delivery of RNAi therapeutics (2008 · Nature Biotechnology · 被引 1234)
- Multivalent N -Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing (2014 · Journal of the American Chemical Society · 被引 1103)
- Mechanisms and optimization of in vivo delivery of lipophilic siRNAs (2007 · Nature Biotechnology · 被引 978)
- Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates (2008 · Proceedings of the National Academy of Sciences · 被引 641)
- Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc–siRNA conjugates (2017 · Nucleic Acids Research · 被引 277)