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Tracy Zimmermann

机构:Alnylam Pharmaceuticals (United States)

发表论文 17 篇 · 总被引 6200 次 · h-index 13

代表论文

  • RNAi-mediated gene silencing in non-human primates (2006 · Nature · 被引 1350)
  • A combinatorial library of lipid-like materials for delivery of RNAi therapeutics (2008 · Nature Biotechnology · 被引 1234)
  • Multivalent N -Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing (2014 · Journal of the American Chemical Society · 被引 1103)
  • Mechanisms and optimization of in vivo delivery of lipophilic siRNAs (2007 · Nature Biotechnology · 被引 978)
  • Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates (2008 · Proceedings of the National Academy of Sciences · 被引 641)
  • Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc–siRNA conjugates (2017 · Nucleic Acids Research · 被引 277)