John R. Murphy

机构：Pfizer (United Kingdom) · ORCID：0000-0002-9360-4481

发表论文 230 篇 · 总被引 9707 次 · h-index 48

代表论文

• Mechanism of Diphtheria Toxin Catalytic Domain Delivery to the Eukaryotic Cell Cytosol and the Cellular Factors that Directly Participate in the Process (2011 · Toxins · 被引 178)
• Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma (2019 · Proceedings of the National Academy of Sciences · 被引 81)
• Characterisation and Deposition Studies of Recrystallised Lactose from Binary Mixtures of Ethanol/Butanol for Improved Drug Delivery from Dry Powder Inhalers (2010 · The AAPS Journal · 被引 64)
• Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin (2016 · Journal of Medicinal Chemistry · 被引 56)
• Engineered mannitol as an alternative carrier to enhance deep lung penetration of salbutamol sulphate from dry powder inhaler (2010 · Colloids and Surfaces B Biointerfaces · 被引 54)
• A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol (2005 · Proceedings of the National Academy of Sciences · 被引 51)