Amanda Balesano

机构：Pfizer (United States) · ORCID：0009-0001-7641-1127

发表论文 11 篇 · 总被引 216 次 · h-index 7

代表论文

The Role of Alcohol Dehydrogenase in Drug Metabolism: Beyond Ethanol Oxidation (2021 · The AAPS Journal · 被引 70)
Discovery of SARS-CoV-2 papain-like protease (PL pro ) inhibitors with efficacy in a murine infection model (2024 · Science Advances · 被引 55)
The Comparison of Machine Learning and Mechanistic In Vitro–In Vivo Extrapolation Models for the Prediction of Human Intrinsic Clearance (2023 · Molecular Pharmaceutics · 被引 30)
Defining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting Approach (2022 · Drug Metabolism and Disposition · 被引 21)
Discovery of First Branched-Chain Ketoacid Dehydrogenase Kinase (BDK) Inhibitor Clinical Candidate PF-07328948 (2024 · Journal of Medicinal Chemistry · 被引 13)
An Improved Method for Cytochrome P450 Reaction Phenotyping Using a Sequential Qualitative-Then-Quantitative Approach (2022 · Drug Metabolism and Disposition · 被引 11)