Hiroaki Mitsuya

机构：National Center for Global Health and Medicine, National Cancer Institute, Kumamoto University · ORCID：0000-0001-9274-3853

发表论文 790 篇 · 总被引 34236 次 · h-index 85

代表论文

Structural and virologic mechanism of the emergence of resistance to M pro inhibitors in SARS-CoV-2 (2024 · Proceedings of the National Academy of Sciences · 被引 18)
Exploration of P1 and P4 modifications of nirmatrelvir: Design, synthesis, biological evaluation, and X-ray structural studies of SARS-CoV-2 Mpro inhibitors (2024 · European Journal of Medicinal Chemistry · 被引 15)
An orally available P1′-5-fluorinated Mpro inhibitor blocks SARS-CoV-2 replication without booster and exhibits high genetic barrier (2024 · PNAS Nexus · 被引 9)
Azapeptide-BasedSARS-CoV-2 Main Protease Inhibitors:Design, Synthesis, Enzyme Inhibition, Structural Determination, andAntiviral Activity (2025 · Journal of Medicinal Chemistry · 被引 5)
Naphthalen-1-ylethanamine–containing small molecule inhibitors of the papain-like protease of SARS-CoV-2 (2024 · European Journal of Medicinal Chemistry · 被引 4)
Discovery of Potent DAG-Lactone Derivatives as HIV Latency Reversing Agents (2024 · ACS Infectious Diseases · 被引 4)