Irina Shlaifer

机构：Montreal Neurological Institute and Hospital, McGill University · ORCID：0000-0002-3737-268X

发表论文 64 篇 · 总被引 537 次 · h-index 13

代表论文

• Modeling Parkinson’s disease pathology in human dopaminergic neurons by sequential exposure to α-synuclein fibrils and proinflammatory cytokines (2024 · Nature Neuroscience · 被引 58)
• An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders (2024 · Molecular Neurodegeneration · 被引 17)
• USP19 deubiquitinase inactivation regulates α-synuclein ubiquitination and inhibits accumulation of Lewy body-like aggregates in mice (2023 · npj Parkinson s Disease · 被引 17)
• Neuroanatomical and cognitive biomarkers of alpha‐synuclein propagation in a mouse model of synucleinopathy prior to onset of motor symptoms (2023 · Journal of Neurochemistry · 被引 15)
• A genome-wide CRISPR/Cas9 screen identifies genes that regulate the cellular uptake of α-synuclein fibrils by modulating heparan sulfate proteoglycans (2023 · bioRxiv (Cold Spring Harbor Laboratory) · 被引 9)
• α-Synuclein purification significantly impacts seed amplification assay performance and consistency (2025 · Acta Neuropathologica Communications · 被引 6)