Jason D. Graci

机构：PTC Therapeutics (United States) · ORCID：0000-0002-6329-9164

发表论文 34 篇 · 总被引 1644 次 · h-index 19

代表论文

• RNA Virus Population Diversity, an Optimum for Maximal Fitness and Virulence (2014 · Journal of Biological Chemistry · 被引 103)
• Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties (2018 · Molecular Cancer Therapeutics · 被引 87)
• Small molecule splicing modifiers with systemic HTT-lowering activity (2021 · Nature Communications · 被引 86)
• The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines (2020 · Virus Research · 被引 74)
• Therapeutically Targeting Rna Viruses Via Lethal Mutagenesis (2008 · Future Virology · 被引 69)
• Mutational Robustness of an RNA Virus Influences Sensitivity to Lethal Mutagenesis (2011 · Journal of Virology · 被引 63)