Szymon Kłossowski

机构：University of Michigan

发表论文 40 篇 · 总被引 971 次 · h-index 14

代表论文

• Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia (2019 · Journal of Clinical Investigation · 被引 246)
• Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia. (2020 · PubMed · 被引 142)
• Complexity of Blocking Bivalent Protein–Protein Interactions: Development of a Highly Potent Inhibitor of the Menin–Mixed-Lineage Leukemia Interaction (2018 · Journal of Medicinal Chemistry · 被引 63)
• Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of PEG10 and Blocks Hepatocellular Carcinoma (2017 · Molecular Cancer Therapeutics · 被引 54)
• Menin regulates the serine biosynthetic pathway in Ewing sarcoma (2018 · The Journal of Pathology · 被引 51)
• Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity (2021 · Nature Communications · 被引 43)