Hangchen Hu

机构：Chinese Academy of Sciences, Shanghai Institute of Materia Medica, State Key Laboratory of Drug Research · ORCID：0000-0002-1063-9292

发表论文 17 篇 · 总被引 185 次 · h-index 10

代表论文

• Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein Inhibitors (2024 · Journal of the American Chemical Society · 被引 26)
• De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS (2025 · Nature Communications · 被引 21)
• Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches (2023 · Chemical Science · 被引 19)
• Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease (2023 · International Journal of Molecular Sciences · 被引 18)
• Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS‐CoV‐2 Papain‐Like Protease** (2022 · Angewandte Chemie International Edition · 被引 18)
• Structure-Based Survey of the Binding Modes of BACE1 Inhibitors (2018 · ACS Chemical Neuroscience · 被引 18)