Christopher J. Helal
ORCID：0000-0002-9091-2091
发表论文 84 篇 · 总被引 4884 次 · h-index 32
代表论文
- A platform for automated nanomole-scale reaction screening and micromole-scale synthesis in flow (2018 · Science · 被引 506)
- Design and Selection Parameters to Accelerate the Discovery of Novel Central Nervous System Positron Emission Tomography (PET) Ligands and Their Application in the Development of a Novel Phosphodiesterase 2A PET Ligand (2013 · Journal of Medicinal Chemistry · 被引 207)
- Introduction of a Crystalline, Shelf-Stable Reagent for the Synthesis of Sulfur(VI) Fluorides (2018 · Organic Letters · 被引 143)
- Discovery of the Potent and Selective M1 PAM-AgonistN-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects (2016 · Journal of Medicinal Chemistry · 被引 86)
- Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation (2018 · Journal of Medicinal Chemistry · 被引 82)
- High‐Throughput Ligand Screening Enables the Enantioselective Conjugate Borylation of Cyclobutenones to Access Synthetically Versatile Tertiary Cyclobutylboronates (2019 · Angewandte Chemie International Edition · 被引 76)