Charles E. de Bock

机构：Children's Oncology Group, Cancer Institute of New South Wales, UNSW Sydney, Children's Cancer Institute Australia · ORCID：0000-0001-5182-8535

发表论文 191 篇 · 总被引 3448 次 · h-index 31

代表论文

PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma (2024 · Journal of Clinical Investigation · 被引 44)
PU.1 eviction at lymphocyte-specific chromatin domains mediates glucocorticoid response in acute lymphoblastic leukemia (2024 · Nature Communications · 被引 7)
The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia (2024 · Blood Cancer Journal · 被引 6)
FAT1 functions as an oncogenic driver in triple negative breast cancer through AKT pathway-driven effects on the matrisome (2025 · International Journal of Biological Sciences · 被引 4)
A novel MYB::PAIP1 oncogenic fusion in pediatric blastic plasmacytoid dendritic cell neoplasm (BPDCN) is dependent on BCL2 expression and is sensitive to venetoclax (2024 · HemaSphere · 被引 4)
Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for acute myeloid leukemia cell self-renewal (2025 · Leukemia · 被引 2)