Alexandre Orthwein

机构：Emory University · ORCID：0000-0002-7350-3413

发表论文 97 篇 · 总被引 5042 次 · h-index 23

代表论文

EIF4A inhibition targets bioenergetic homeostasis in AML MOLM-14 cells in vitro and in vivo and synergizes with cytarabine and venetoclax (2022 · Journal of Experimental & Clinical Cancer Research · 被引 38)
Combination radiation and αPD-L1 enhance tumor control by stimulating CD8+ PD-1+ TCF-1+ T cells in the tumor-draining lymph node (2025 · Nature Communications · 被引 21)
An E3 ubiquitin ligase localization screen uncovers DTX2 as a novel ADP-ribosylation-dependent regulator of DNA double-strand break repair (2024 · Journal of Biological Chemistry · 被引 21)
FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair (2023 · Science Advances · 被引 16)
The mitochondrial pyruvate carrier complex potentiates the efficacy of proteasome inhibitors in multiple myeloma (2023 · Blood Advances · 被引 13)
B cell-specific knockout of AID protects against atherosclerosis (2023 · Scientific Reports · 被引 6)