Dominique Perrin

ORCID：0000-0003-1290-1888

发表论文 189 篇 · 总被引 5629 次 · h-index 36

代表论文

• Comparison of methods for the prediction of human clearance from hepatocyte intrinsic clearance for a set of reference compounds and an external evaluation set (2016 · Xenobiotica · 被引 37)
• IOA-244 is a Non–ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance (2023 · Cancer Research Communications · 被引 34)
• Brain penetration and efficacy of tepotinib in orthotopic patient-derived xenograft models of MET-driven non-small cell lung cancer brain metastases (2021 · Lung Cancer · 被引 27)
• Comparative analysis of YAP/TEAD inhibitors in 2D and 3D cultures of primary human hepatocytes reveals a novel non-canonical mechanism of CYP induction (2023 · Biochemical Pharmacology · 被引 13)
• Assessment of the potential of the MET inhibitor tepotinib to affect the pharmacokinetics of CYP3A4 and P-gp substrates (2023 · Investigational New Drugs · 被引 7)
• Insights into Praziquantel Metabolism and Potential Enantiomeric Cytochrome P450–Mediated Drug-Drug Interaction (2020 · Drug Metabolism and Disposition · 被引 7)