Emmanuel Christian Patin

机构：Institute of Cancer Research, Imperial College London · ORCID：0000-0001-5390-5733

发表论文 78 篇 · 总被引 2357 次 · h-index 20

代表论文

• A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death (2024 · Immunity · 被引 89)
• Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation (2023 · Journal of Clinical Investigation · 被引 55)
• Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy (2024 · Nature Communications · 被引 20)
• Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling (2024 · Journal for ImmunoTherapy of Cancer · 被引 15)
• Tumor control and immune activation through palliative irradiation and ATR inhibition, PATRIOT Part C: a phase Ib trial (2025 · Nature Communications · 被引 12)
• The PARP inhibitor talazoparib synergizes with reovirus to induce cancer killing and tumour control in vivo in mouse models (2025 · Nature Communications · 被引 7)