Martina Schaefer

机构：Nuvisan (Germany) · ORCID：0000-0003-3640-6435

发表论文 48 篇 · 总被引 715 次 · h-index 11

代表论文

• Discovery and SAR of Novel 2,3‐Dihydroimidazo[1,2‐c]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80‐6946) (2016 · ChemMedChem · 被引 120)
• Compartmentalization of a unique ADP/ATP carrier protein SFEC (Sperm Flagellar Energy Carrier, AAC4) with glycolytic enzymes in the fibrous sheath of the human sperm flagellar principal piece (2006 · Developmental Biology · 被引 108)
• Structure of Cinaciguat (BAY 58–2667) Bound to Nostoc H-NOX Domain Reveals Insights into Heme-mimetic Activation of the Soluble Guanylyl Cyclase (2010 · Journal of Biological Chemistry · 被引 100)
• Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042) (2021 · Journal of Medicinal Chemistry · 被引 67)
• Allosteric Inhibition as a New Mode of Action for BAY 1213790, a Neutralizing Antibody Targeting the Activated Form of Coagulation Factor XI (2019 · Journal of Molecular Biology · 被引 67)
• Insights into BAY 60-2770 Activation and S-Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H-NOX Domain Complexes (2013 · Biochemistry · 被引 59)