Jithesh Kottur

机构：Icahn School of Medicine at Mount Sinai · ORCID：0000-0002-8075-3883

发表论文 46 篇 · 总被引 897 次 · h-index 16

代表论文

• A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models (2021 · Science Translational Medicine · 被引 158)
• H19 influenza A virus exhibits species-specific MHC class II receptor usage (2024 · Cell Host & Microbe · 被引 97)
• Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction (2018 · Nucleic Acids Research · 被引 79)
• Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic (2022 · Oncogene · 被引 58)
• Discovery of Potent and Selective WDR5 Proteolysis Targeting Chimeras as Potential Therapeutics for Pancreatic Cancer (2023 · Journal of Medicinal Chemistry · 被引 51)
• High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development (2022 · Nature Structural & Molecular Biology · 被引 37)