Aloysius T. Nchinda

机构：University of Cape Town, Discovery Centre

发表论文 43 篇 · 总被引 1209 次 · h-index 19

代表论文

• UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria (2018 · Antimicrobial Agents and Chemotherapy · 被引 136)
• 3,5-Diaryl-2-aminopyridines as a Novel Class of Orally Active Antimalarials Demonstrating Single Dose Cure in Mice and Clinical Candidate Potential (2012 · Journal of Medicinal Chemistry · 被引 134)
• Novel Orally Active Antimalarial Thiazoles (2011 · Journal of Medicinal Chemistry · 被引 81)
• Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle (2016 · Journal of Medicinal Chemistry · 被引 59)
• Structure–Activity-Relationship Studies around the 2-Amino Group and Pyridine Core of Antimalarial 3,5-Diarylaminopyridines Lead to a Novel Series of Pyrazine Analogues with Oral in Vivo Activity (2013 · Journal of Medicinal Chemistry · 被引 50)
• Medicinal Chemistry Optimization of Antiplasmodial Imidazopyridazine Hits from High Throughput Screening of a SoftFocus Kinase Library: Part 1 (2014 · Journal of Medicinal Chemistry · 被引 48)