Kevin Parris

机构：Pfizer (United States)

发表论文 80 篇 · 总被引 2270 次 · h-index 27

代表论文

Discovery of Cytotoxic Dolastatin 10 Analogues with N-Terminal Modifications (2014 · Journal of Medicinal Chemistry · 被引 134)
Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose (2020 · Journal of Medicinal Chemistry · 被引 78)
Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors (2015 · Journal of Medicinal Chemistry · 被引 78)
Three-Dimensional Structure and Biophysical Characterization of Staphylococcus aureus Cell Surface Antigen–Manganese Transporter MntC (2013 · Journal of Molecular Biology · 被引 63)
Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody (2016 · mAbs · 被引 53)
Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK) (2017 · Journal of Medicinal Chemistry · 被引 50)