Renzhao Gui

机构：Zunyi Medical University, Chinese Academy of Sciences, Shanghai Institute of Materia Medica

发表论文 4 篇 · 总被引 70 次 · h-index 4

代表论文

• Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors (2024 · Journal of Medicinal Chemistry · 被引 21)
• Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia (2022 · Leukemia · 被引 21)
• Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia (2023 · European Journal of Medicinal Chemistry · 被引 15)
• Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity (2024 · Journal of Medicinal Chemistry · 被引 13)