Lei Jia
机构：Pfizer (United States)
发表论文 3 篇 · 总被引 1033 次 · h-index 2
代表论文
- Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK) (2011 · Journal of Medicinal Chemistry · 被引 928)
- Discovery of a Novel Class of Exquisitely Selective Mesenchymal-Epithelial Transition Factor (c-MET) Protein Kinase Inhibitors and Identification of the Clinical Candidate 2-(4-(1-(Quinolin-6-ylmethyl)-1 H -[1,2,3]triazolo[4,5- b ]pyrazin-6-yl)-1 H -pyrazol-1-yl)ethanol (PF-04217903) for the Treatment of Cancer (2012 · Journal of Medicinal Chemistry · 被引 105)
- Crystal structures of diverse inhibitors bound to c-Met kinase reveal multiple protein conformations (2008)