Aijia Yu

机构：WuXi AppTec (China)

发表论文 10 篇 · 总被引 190 次 · h-index 5

代表论文

• Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors (2015 · Journal of Medicinal Chemistry · 被引 78)
• Discovery of SARS-CoV-2 papain-like protease (PL pro ) inhibitors with efficacy in a murine infection model (2024 · Science Advances · 被引 55)
• Leveraging of Rifampicin-Dosed Cynomolgus Monkeys to Identify Bile Acid 3-O-Sulfate Conjugates as Potential Novel Biomarkers for Organic Anion-Transporting Polypeptides (2017 · Drug Metabolism and Disposition · 被引 43)
• Discovery of SARS-CoV-2 papain-like protease (PL pro ) inhibitors with efficacy in a murine infection model (2024 · bioRxiv (Cold Spring Harbor Laboratory) · 被引 6)
• Synthesis of Deuterated Heterocycles with Me 2 NCD(OMe) 2 and Evaluation of the Products for Metabolism by Aldehyde Oxidase (2022 · ACS Medicinal Chemistry Letters · 被引 5)
• Utilizing CYP2D6 and BACE1 Structure Complexes to Reduce Risk of Drug-Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors (2015 · 被引 1)