Dilinie P. Fernando

发表论文 36 篇 · 总被引 826 次 · h-index 16

代表论文

Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H -indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy (2016 · Journal of Medicinal Chemistry · 被引 119)
Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose (2020 · Journal of Medicinal Chemistry · 被引 78)
Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate (2014 · ACS Medicinal Chemistry Letters · 被引 71)
Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases (2015 · Journal of Medicinal Chemistry · 被引 58)
Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting (2020 · Journal of Medicinal Chemistry · 被引 31)
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor (2013 · Bioorganic & Medicinal Chemistry Letters · 被引 27)