Ahron J. Flowers

机构：University of Pennsylvania · ORCID：0000-0002-5579-1351

发表论文 21 篇 · 总被引 500 次 · h-index 8

代表论文

• Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells (2024 · Cancer Cell · 被引 112)
• LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity (2024 · Cell · 被引 108)
• Patient-derived melanoma organoid models facilitate the assessment of immunotherapies (2023 · EBioMedicine · 被引 96)
• Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity (2023 · Cell Reports · 被引 79)
• An autologous humanized patient-derived-xenograft platform to evaluate immunotherapy in ovarian cancer (2019 · Gynecologic Oncology · 被引 53)
• Engineered extracellular vesicles with DR5 agonistic scFvs simultaneously target tumor and immunosuppressive stromal cells (2025 · Science Advances · 被引 24)