James E. Dunford

机构：Nuffield Orthopaedic Centre, University of Oxford, Oxford BioMedica (United Kingdom) · ORCID：0000-0002-9932-4042

发表论文 141 篇 · 总被引 5061 次 · h-index 33

代表论文

• Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming (2019 · Nature Chemical Biology · 被引 103)
• Bisphosphonates: The role of chemistry in understanding their biological actions and structure-activity relationships, and new directions for their therapeutic use (2021 · Bone · 被引 96)
• Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity (2018 · Journal of Medicinal Chemistry · 被引 91)
• Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases (2023 · Genome Medicine · 被引 80)
• The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants (2015 · Bone · 被引 63)
• GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates (2017 · New England Journal of Medicine · 被引 61)