Sandra R. Bacman

机构：University of Miami · ORCID：0000-0001-8701-6010

发表论文 73 篇 · 总被引 3595 次 · h-index 28

代表论文

• MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation (2018 · Nature Medicine · 被引 285)
• The mitochondrial DNA polymerase gamma degrades linear DNA fragments precluding the formation of deletions (2018 · Nature Communications · 被引 136)
• Mitochondrial targeted meganuclease as a platform to eliminate mutant mtDNA in vivo (2021 · Nature Communications · 被引 93)
• mitoTev‐TALE: a monomeric DNA editing enzyme to reduce mutant mitochondrial DNA levels (2018 · EMBO Molecular Medicine · 被引 82)
• Efficient elimination of MELAS-associated m.3243G mutant mitochondrial DNA by an engineered mitoARCUS nuclease (2023 · Nature Metabolism · 被引 45)
• Myopathy reversion in mice after restauration of mitochondrial complex I (2020 · EMBO Molecular Medicine · 被引 45)