Matthew J. Graneto

机构：Pfizer (United States)

发表论文 25 篇 · 总被引 4117 次 · h-index 17

代表论文

• Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1 H -pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib) (1997 · Journal of Medicinal Chemistry · 被引 1967)
• 4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, Valdecoxib: A Potent and Selective Inhibitor of COX-2 (2000 · Journal of Medicinal Chemistry · 被引 643)
• The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life (2010 · Bioorganic & Medicinal Chemistry Letters · 被引 343)
• A Selective IKK-2 Inhibitor Blocks NF-κB-dependent Gene Expression in Interleukin-1β-stimulated Synovial Fibroblasts (2003 · Journal of Biological Chemistry · 被引 274)
• N -[[(5-Methyl-3-phenylisoxazol-4-yl)- phenyl]sulfonyl]propanamide, Sodium Salt, Parecoxib Sodium: A Potent and Selective Inhibitor of COX-2 for Parenteral Administration (2000 · Journal of Medicinal Chemistry · 被引 214)
• Synthesis and activity of sulfonamide-substituted 4,5-diaryl thiazoles as selective cyclooxygenase-2 inhibitors (1999 · Bioorganic & Medicinal Chemistry Letters · 被引 159)