Raja Sekhar Nirujogi

机构：University of Dundee, MRC Protein Phosphorylation and Ubiquitylation Unit, Aligning Science Across Parkinson's, Medical Research Council · ORCID：0000-0002-3177-8566

发表论文 171 篇 · 总被引 7261 次 · h-index 36

代表论文

• Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood–Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2 (2022 · Journal of the American Chemical Society · 被引 185)
• Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies (2021 · PLoS ONE · 被引 98)
• R1441G but not G2019S mutation enhances LRRK2 mediated Rab10 phosphorylation in human peripheral blood neutrophils (2021 · Acta Neuropathologica · 被引 86)
• Golgi-IP, a tool for multimodal analysis of Golgi molecular content (2023 · Proceedings of the National Academy of Sciences · 被引 75)
• Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1 (2021 · Science Advances · 被引 75)
• Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson’s disease in midbrain dopaminergic neurons (2022 · npj Parkinson s Disease · 被引 68)