Xun Gui

机构：Bioscience (China) · ORCID：0000-0002-5070-3527

发表论文 89 篇 · 总被引 3079 次 · h-index 21

代表论文

• Cardiolipin-mimic lipid nanoparticles without antibody modification delivered senolytic in vivo CAR-T therapy for inflamm-aging (2025 · Cell Reports Medicine · 被引 41)
• Preclinical development of a novel CCR8/CTLA-4 bispecific antibody for cancer treatment by disrupting CTLA-4 signaling on CD8 T cells and specifically depleting tumor-resident Tregs (2024 · Cancer Immunology Immunotherapy · 被引 15)
• IL-11/IL-11R signal inhibition by 9MW3811 remodels immune tumor microenvironment and enhances anti-tumor efficacy of PD-1 blockade (2025 · npj Precision Oncology · 被引 14)
• Specifically blocking αvβ8-mediated TGF-β signaling to reverse immunosuppression by modulating macrophage polarization (2025 · Journal of Experimental & Clinical Cancer Research · 被引 13)
• Overcoming multidrug resistance in gastrointestinal cancers with a CDH17-targeted ADC conjugated to a DNA topoisomerase inhibitor (2025 · Cell Reports Medicine · 被引 12)
• Cardiolipin-mimic lipid nanoparticles without antibody modification delivered senolytic in-vivo CAR-T therapy for inflamm-aging (2024 · bioRxiv (Cold Spring Harbor Laboratory) · 被引 6)