Dazheng Ling

机构：East China University of Science and Technology

发表论文 9 篇 · 总被引 298 次 · h-index 8

代表论文

• Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer’s Disease (2017 · ACS Chemical Neuroscience · 被引 64)
• A novel multistage antiplasmodial inhibitor targeting Plasmodium falciparum histone deacetylase 1 (2020 · Cell Discovery · 被引 57)
• Discovery of Novel Plasmodium falciparum HDAC1 Inhibitors with Dual-Stage Antimalarial Potency and Improved Safety Based on the Clinical Anticancer Drug Candidate Quisinostat (2021 · Journal of Medicinal Chemistry · 被引 45)
• Drug Repurposing of Quisinostat to Discover Novel Plasmodium falciparum HDAC1 Inhibitors with Enhanced Triple-Stage Antimalarial Activity and Improved Safety (2022 · Journal of Medicinal Chemistry · 被引 35)
• Melting Point Distribution Analysis of Globally Approved and Discontinued Drugs: A Research for Improving the Chance of Success of Drug Design and Discovery (2016 · ChemistryOpen · 被引 34)
• Novel Tadalafil Derivatives Ameliorates Scopolamine-Induced Cognitive Impairment in Mice via Inhibition of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) (2018 · ACS Chemical Neuroscience · 被引 29)