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Patrick Alfryn Lewis

机构:University of London, Royal Veterinary College, NIHR Queen Square Dementia Biomedical Research Unit, National Hospital for Neurology and Neurosurgery, UCL Queen Square Institute of Neurology, University College London · ORCID:0000-0003-4537-0489

发表论文 316 篇 · 总被引 22922 次 · h-index 56

代表论文

  • Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease (2023 · Nature Genetics · 被引 287)
  • GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis (2025 · Science Advances · 被引 14)
  • Common genetic risk for Parkinson's disease and dysfunction of the endo-lysosomal system (2024 · Philosophical Transactions of the Royal Society B Biological Sciences · 被引 10)
  • GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis (2025 · bioRxiv (Cold Spring Harbor Laboratory) · 被引 9)
  • Transcriptomics and weighted protein network analyses of the LRRK2 protein interactome reveal distinct molecular signatures for sporadic and LRRK2 Parkinson’s Disease (2024 · npj Parkinson s Disease · 被引 7)
  • Insights into ancestral diversity in Parkinson’s disease risk: a comparative assessment of polygenic risk scores (2025 · npj Parkinson s Disease · 被引 6)