Ryan L. Powles

机构：Bristol-Myers Squibb (Germany), Bristol-Myers Squibb (Belgium) · ORCID：0009-0006-3706-9281

发表论文 48 篇 · 总被引 1033 次 · h-index 10

代表论文

• DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell–mediated antitumor immunity (2023 · Science Translational Medicine · 被引 29)
• Discovery of BMS-986408, a First-In-Class Dual DGKα and DGKζ Inhibitor that Unleashes PD-1 Checkpoint and CAR T-cell Immunotherapies (2025 · Cancer Immunology Research · 被引 9)
• Covalent inhibitor design confers activity against both GDP- and GTP-bound forms of KRAS G12C (2026 · Nature Communications · 被引 3)
• Data from Discovery of BMS-986408, a First-In-Class Dual DGKα and DGKζ Inhibitor that Unleashes PD-1 Checkpoint and CAR T-cell Immunotherapies (2025)
• Table S2 from Discovery of BMS-986408, a First-In-Class Dual DGKα and DGKζ Inhibitor that Unleashes PD-1 Checkpoint and CAR T-cell Immunotherapies (2025)
• Figure S3 from Discovery of BMS-986408, a First-In-Class Dual DGKα and DGKζ Inhibitor that Unleashes PD-1 Checkpoint and CAR T-cell Immunotherapies (2025)